# Diosmin in Nigeria

Diosmin has 3 active NAFDAC registrations in our October 2026 copy of the register, from 2 registration holders; 2 further listings have lapsed.

- Source: https://ogbogwu.com/drugs/diosmin/
- Drug class: Flavonoid venotonic and vascular protector (Veins & Circulation)
- Also known as: Daflon, Phlebodia, Diosmin-hesperidin, Micronised purified flavonoid fraction, MPFF, Venotonic
- Prescription required: no
- Last updated: September 2026

## Price in Nigeria

Our sampled online listings held no stable diosmin price this cycle, so we quote none. Daflon 500 mg sells as a 30- or 60-tablet pack from pharmacies, with the imported originator priced well above the locally made 150 mg tablets; a course for piles is a week, a course for tired legs is months, so the pack size matters more than the unit price. Ask a licensed pharmacy, and check the pack's NAFDAC number before paying.

## What is Diosmin?

Diosmin is a plant flavonoid, refined from citrus peel, taken as a tablet to strengthen vein walls and reduce the leakiness and inflammation behind two very common complaints: piles (haemorrhoids) and heavy, swollen, aching legs from poor vein return. It does not thin the blood and it is not a painkiller — it works slowly on the vessel itself, which is why the leg-symptom course runs for months while the piles course is a short, high-dose burst.

In Nigeria the name most people know is Daflon, Servier's diosmin-plus-hesperidin tablet (the micronised purified flavonoid fraction, or MPFF), registered here as Daflon 500 mg and Daflon 1000 mg. Phlebodia 600 mg, the French single-ingredient diosmin tablet imported by Phillips Pharmaceuticals, is the other imported name people ask for. There are also locally made 150 mg diosmin tablets — Dr. Meyer's Pilex from Farmex Meyer, and Pilicon from Therapeutic Laboratories — sold mostly for piles.

One thing worth knowing before you buy: not every name on this list is currently registered. In our copy of the NAFDAC register, Daflon 500 mg and Dr. Meyer's Pilex are Active, while the Phlebodia and Pilicon registrations are recorded as Inactive, their five-year terms having run out in early 2026. Inactive is a renewal question for the holder, not a verdict on the tablets, but a pack whose number has lapsed is a pack to buy with more care.

## What is Diosmin used for?

- Acute haemorrhoid (piles) attacks — pain, swelling and bleeding — as a short course
- Chronic venous insufficiency: heavy, tired, aching or swollen legs, night cramps and varicose veins
- Reducing leg swelling and skin changes in long-standing venous disease, alongside compression stockings and leg elevation

## Dosage

Always follow a doctor's or pharmacist's instructions; this is general reference information.

- Adults: For piles, packs give a short high-dose course — with Daflon 500 mg, typically six tablets a day for four days then four a day for three days, taken with meals. For heavy or swollen legs the dose is much lower and much longer: Daflon 500 mg one tablet morning and evening, or Daflon 1000 mg once a day, or Phlebodia 600 mg one tablet each morning before breakfast, for one to three months at a time. The locally made 150 mg tablets follow their own pack directions. Follow the leaflet for the brand you have; the numbers differ because the tablets do.
- Children: Not for children. There is no established dose, and swollen legs or rectal bleeding in a child needs a doctor, not a vein tablet.
- Elderly: No dose change is needed, and older adults are the main users for leg symptoms. Do make sure new ankle swelling has been checked for heart, kidney or liver causes before treating it as a vein problem.

Take with food to reduce stomach upset. Diosmin treats the symptoms of piles; it does not cure them. The habits do — fibre, water, not straining and not sitting on the toilet for long — and a stool softener for the first week helps more than a second pack of tablets.

## Side effects

Common: Stomach upset — mild diarrhoea, indigestion, nausea or stomach pain, usually at the high piles dose; Headache; Dizziness or a general feeling of being unwell.

Serious (seek medical help immediately): Allergic reaction: rash, itching, hives, or swelling of the face or lips — stop and seek help; Continued rectal bleeding despite treatment — not a drug side effect, but a reason to stop self-treating and be examined.

When to see a doctor: See a doctor if piles bleed for more than a week, if bleeding is dark or mixed into the stool, if you are over 45 and this is new, or if there is weight loss or a change in bowel habit: those need examination to rule out something other than piles. For legs, one swollen, hot or painful calf — especially after travel, surgery or childbirth — could be a clot and is an emergency, not a case for a vein tablet.

## Warnings

Do not take if: Known allergy to diosmin, hesperidin or any component of the tablet; Rectal bleeding that has not been assessed — treat the diagnosis, not the symptom; A suspected deep vein clot (one hot, swollen, painful leg) — this needs urgent medical care, and diosmin is not treatment for it.

Interactions: No clinically important drug interactions are documented. Diosmin does not thin the blood and can be taken alongside blood-pressure medicines and painkillers; It does not replace compression stockings or leg elevation for venous disease — they work together.

Pregnancy & breastfeeding: Piles are extremely common in late pregnancy and diosmin is widely used for them; animal studies show no harm to the baby and there is long experience of use, but take it on a doctor's or pharmacist's advice rather than off the shelf. While breastfeeding it is not recommended, as it is not known whether it passes into milk.

## Brands in Nigeria

Well-known NAFDAC-registered brands: Daflon (Servier, made in Egypt); Dr. Meyer's Pilex (Farmex Meyer Limited, made in Nigeria); Phlebodia (Phillips Pharmaceuticals (Nigeria) Limited, made in France); Pilicon (Therapeutic Laboratories Nigeria Limited, made in Nigeria).
Full searchable brand list: https://ogbogwu.com/drugs/diosmin/brands/

## How to verify it is genuine

1. Check the pack for its NAFDAC registration number — Daflon 500 mg tablets carry 04-6857 and Dr. Meyer's Pilex 04-7020, both recorded as Active in our copy of the register
2. Phlebodia 600 mg (B4-5563) and Pilicon (A4-0582) are recorded as Inactive in our copy, their registrations having expired in early 2026. That is a renewal matter for the holder, not proof a pack is fake, but confirm the current status on the official Greenbook before a large purchase
3. Enter the number in our free NAFDAC checker and confirm the product name and holder match what is printed on the pack
4. Daflon is imported and priced accordingly, which makes it a counterfeit target — buy from a registered pharmacy, and be suspicious of Daflon sold loose or far below pharmacy price

Verify any NAFDAC number free (no login): https://ogbogwu.com/nafdac-checker/

## FAQs

### Is Daflon NAFDAC approved in Nigeria?

Yes — our copy of the NAFDAC register lists Daflon 500 mg tablets under registration 04-6857, held by Servier Pharmaceuticals Development Limited, with status Active, and a separate listing for Daflon 1000 mg. Check the number printed on your pack against its own listing in our free NAFDAC checker before you buy.

### Is Phlebodia registered with NAFDAC?

It was. Our copy of the register records Phlebodia Tablets 600 mg under B4-5563, held by Phillips Pharmaceuticals (Nigeria) Limited, with status Inactive — the registration expired in February 2026 and had not been renewed when our copy was taken. Listings can lag renewals, so confirm the current status on the official Greenbook. Until then, Daflon is the imported diosmin whose registration is current.

### How long does diosmin take to work for piles?

Most people feel less pain and swelling within two to three days of the high-dose course, with bleeding settling over the week. If a flare has not eased after seven days of treatment, or keeps coming back, be examined — persistent piles have other treatments, and persistent bleeding may not be piles at all.

### Can I take diosmin every day for my legs?

Yes, that is how it is used for heavy or swollen legs: a low daily dose for one to three months, repeated as needed, together with compression stockings, walking and putting your feet up at the end of the day. It is not a blood thinner and does not need monitoring, but new one-sided leg swelling should be checked for a clot before you start.

## Sources

- NAFDAC Greenbook (official register of approved products in Nigeria)
- British National Formulary (BNF)
- Nigerian Standard Treatment Guidelines (Federal Ministry of Health)