# Ferrous Sulfate in Nigeria

Ferrous Sulfate has 18 active NAFDAC registrations in our October 2026 copy of the register, from 15 registration holders; 12 further listings have lapsed.

- Source: https://ogbogwu.com/drugs/ferrous-sulfate/
- Drug class: Iron supplement (haematinic) (Vitamins & Supplements)
- Also known as: Iron tablets, Ferrous sulphate
- Prescription required: no
- On the WHO Model List of Essential Medicines
- Last updated: October 2026

## Price in Nigeria

As of October 2026, a pack of 28–30 ferrous sulfate tablets sells for about ₦5,750 online in Nigeria (₦63–₦215 a tablet, strip or bulk pack) at three online pharmacies; syrup ₦5,750–₦6,450; packs of 100–120 ₦6,250–₦20,625. Open-market prices (e.g. Idumota, Ogbogwu) are often lower.

## What is Ferrous Sulfate?

Ferrous sulfate is an iron supplement used to prevent and treat iron deficiency anaemia, a condition that is alarmingly prevalent in Nigeria. According to health surveys, over 60% of Nigerian children under five and approximately 50% of pregnant women suffer from some degree of anaemia, with iron deficiency being the most common cause. In everyday Nigerian language, iron supplements are widely referred to as 'blood tonic' or 'blood builder,' and this term is so deeply embedded in local healthcare vocabulary that many Nigerians will walk into a pharmacy and ask specifically for 'blood tonic' rather than iron tablets. From the busy pharmacies of Ikeja and Surulere in Lagos to health centres in Maiduguri and Sokoto, ferrous sulfate and its related iron formulations are among the most frequently dispensed supplements in the country.

Iron is an essential mineral that the body needs to produce haemoglobin, the protein in red blood cells responsible for carrying oxygen from the lungs to every tissue and organ in the body. When iron levels are low, the body cannot produce enough healthy red blood cells, leading to anaemia — a condition characterised by fatigue, weakness, pale skin and nails, shortness of breath, dizziness, and reduced ability to concentrate. In Nigeria, iron deficiency anaemia is driven by multiple factors including malaria (which destroys red blood cells), hookworm infections (common in rural areas), poor dietary iron intake, heavy menstrual bleeding in women, and the increased iron demands of pregnancy and breastfeeding. Ferrous sulfate provides elemental iron that the body can use to restore haemoglobin levels and red blood cell production.

Ferrous sulfate is on the WHO Essential Medicines List and is the backbone of Nigeria's antenatal iron programme. It comes as plain 200 mg tablets and capsules (about 65 mg of elemental iron each), as combination capsules with folic acid, vitamin B12 and zinc, and as syrups and drops for children. Our October 2026 copy of the NAFDAC register holds 30 products led by ferrous sulfate, 18 of them with Active registrations, almost all Nigerian-made 200 mg tablets: Fesulf (Therapeutic Laboratories, 04-0476), MeCure's Blood Tone (04-9611), Reasulf (Reagan Remedies, B4-2517) and Embassy's Ferrolab 12 capsules (04-5887) among them. The two names most people ask for by habit are a different story in the register: Fidson's Astyfer (04-2623) is recorded Expired, its registration having run out in October 2023, and Shalina's Hemoforce Plus (A4-9352) Expired since December 2023. Ranferon and Chemiron, two more household names, do not appear in our copy at all. A lapse is a renewal matter for the holder, not proof that a bottle is fake — but a premium paid for a name the register no longer backs is a premium worth questioning.

## What is Ferrous Sulfate used for?

- Treatment of iron deficiency anaemia — the most common type of anaemia in Nigeria, causing fatigue, weakness, pallor, and reduced physical and mental performance
- Prevention of anaemia during pregnancy, when iron requirements increase significantly to support the growing baby and expanded blood volume — routinely prescribed at every antenatal clinic in Nigeria
- Recovery from blood loss due to heavy menstrual periods (menorrhagia), which affects many Nigerian women and is a leading cause of anaemia in women of reproductive age
- Supplementation for children with nutritional anaemia, particularly in areas where dietary iron intake is inadequate or where malaria and hookworm infections are common
- Supporting recovery from anaemia caused by malaria, which destroys red blood cells and is endemic across much of Nigeria
- Post-surgical and post-partum recovery when blood loss has occurred and the body needs to rebuild its iron stores and red blood cell count

## Dosage

Always follow a doctor's or pharmacist's instructions; this is general reference information.

- Adults: For treatment of iron deficiency anaemia: 200mg ferrous sulfate (containing approximately 65mg of elemental iron) two to three times daily. For prevention in pregnancy: 200mg once or twice daily, commonly taken alongside folic acid. Combination products like Ranferon and Chemiron are typically taken as one capsule once or twice daily depending on the severity of anaemia and the specific product.
- Children: Children aged 6-12 years: 200mg ferrous sulfate once daily. Children aged 2-5 years: Iron syrup is preferred — typically 2.5ml to 5ml of ferrous sulfate syrup (25mg elemental iron per 5ml) once or twice daily. Infants from 6 months: Iron drops as directed by a paediatrician, usually 0.5ml to 1ml daily. Dosing should be based on the child's weight and severity of anaemia — always consult a healthcare provider for children.
- Elderly: Standard adult doses apply, but elderly individuals should start with a lower dose (200mg once daily) and increase as tolerated, as they are more prone to constipation and stomach upset from iron supplements. Elderly patients with chronic kidney disease or other conditions should have their iron supplementation guided by a doctor.

Iron is best absorbed on an empty stomach, ideally taken 30 minutes to 1 hour before meals. However, if it causes stomach upset, it can be taken with a light meal. Taking iron with Vitamin C (such as orange juice or a Vitamin C tablet) significantly enhances absorption. Avoid taking iron with tea, coffee, milk, or calcium supplements as these reduce absorption. Do not take iron tablets at the same time as antacids, tetracycline antibiotics, or ciprofloxacin — space them at least 2 hours apart.

## Side effects

Common: Black or dark-coloured stools — this is completely normal and harmless, caused by unabsorbed iron, but can be alarming to patients who are not warned beforehand; Constipation — one of the most common complaints, especially in pregnant women already prone to constipation; Nausea and stomach cramps, particularly when taken on an empty stomach; Metallic taste in the mouth; Temporary staining of teeth with liquid iron preparations (can be minimised by using a straw or dropper).

Serious (seek medical help immediately): Iron overdose (iron poisoning), which is a medical emergency especially in children — symptoms include severe vomiting, bloody diarrhoea, abdominal pain, and can be fatal if untreated; Severe allergic reaction including rash, swelling, and difficulty breathing (rare with oral forms); Iron overload (haemosiderosis) from chronic excessive supplementation, which can damage the liver, heart, and pancreas; Severe constipation or bowel obstruction in rare cases, particularly in elderly patients.

When to see a doctor: Seek immediate medical attention if a child accidentally swallows iron tablets, as iron poisoning can be fatal in children. Also see a doctor if you experience severe stomach pain, vomiting blood, bloody or tarry stools beyond the normal dark discolouration, persistent severe constipation, or any signs of allergic reaction. If you are taking iron for anaemia and do not feel better after 4-6 weeks of treatment, consult your doctor as further investigation may be needed.

## Warnings

Do not take if: Do not take if you have haemochromatosis (iron overload disorder) or haemosiderosis, as additional iron supplementation could be dangerous; Not recommended for people with peptic ulcer disease or inflammatory bowel disease (ulcerative colitis, Crohn's disease) without medical supervision, as iron can worsen these conditions; Do not give iron supplements intended for adults to children — accidental iron overdose is a leading cause of fatal poisoning in children under 6 years; Avoid in patients receiving repeated blood transfusions, as these already increase iron levels significantly.

Interactions: Tetracycline and doxycycline antibiotics — iron significantly reduces the absorption of these antibiotics; space doses at least 2-3 hours apart; Ciprofloxacin and other fluoroquinolone antibiotics — iron reduces their absorption and effectiveness; take at least 2 hours before or 4 hours after iron; Antacids (aluminium, magnesium, calcium-based) — reduce iron absorption; space at least 2 hours apart; Levothyroxine (thyroid medication) — iron reduces its absorption; take at least 4 hours apart; Tea, coffee, and dairy products — the tannins in tea and coffee and the calcium in dairy significantly reduce iron absorption; avoid consuming these within 1-2 hours of taking iron.

Pregnancy & breastfeeding: Iron supplementation is strongly recommended during pregnancy and is a standard component of antenatal care in Nigeria. The WHO recommends daily iron and folic acid supplementation for all pregnant women to prevent anaemia, which is associated with increased risk of maternal and infant mortality. Ferrous sulfate is safe during pregnancy and breastfeeding at recommended doses. Most Nigerian antenatal clinics prescribe iron from the first antenatal visit and continue throughout pregnancy and for at least 3 months after delivery. Small amounts of iron pass into breast milk, but this is beneficial for the breastfeeding infant and does not cause harm.

## Brands in Nigeria

Well-known NAFDAC-registered brands: Fesulf (Therapeutic Lab. (Nigeria) Limited, made in Nigeria); Ferobin (Fidson Healthcare, made in Nigeria); Ferrolab 12 (Embassy Pharmaceutical and Chemicals Limited, made in India); MeCure's Blood Tone (Me Cure Industries Limited, made in Nigeria); Reasulf (Reagan Remedies, made in Nigeria); Astyfer (Fidson Healthcare, made in India); Hemoforce Plus (Shalina Healthcare Nigeria Limited, made in India).
Full searchable brand list: https://ogbogwu.com/drugs/ferrous-sulfate/brands/

## How to verify it is genuine

1. Check the NAFDAC registration number on the pack. In our October 2026 copy of the register Fesulf (04-0476), Ferobin (04-9722), Ferrolab 12 (04-5887), MeCure's Blood Tone (04-9611) and Reasulf (B4-2517) are Active
2. Verify the NAFDAC number using the official NAFDAC website (www.nafdac.gov.ng) or the NAFDAC mobile verification app available on Android and iOS
3. Purchase iron supplements only from licensed pharmacies or accredited patent medicine stores — counterfeit haematinics have been intercepted by NAFDAC in the past
4. Astyfer (04-2623) and Hemoforce Plus (A4-9352) are recorded Expired in our copy, and Ranferon and Chemiron do not appear in it — confirm the current status of any of these on the official Greenbook before paying a brand premium, and treat a 'blood tonic' with no NAFDAC number at all as the warning sign
5. Check the expiry date before purchase and ensure the packaging is not damaged, faded, or showing signs of tampering
6. Be cautious of unusually cheap iron supplements being sold in open markets like Idumota, Onitsha Main Market, or Head Bridge Market — significantly below-market prices often indicate counterfeit products

Verify any NAFDAC number free (no login): https://ogbogwu.com/nafdac-checker/

## FAQs

### Is Astyfer NAFDAC registered?

Astyfer appears in our October 2026 copy of the NAFDAC register under 04-2623, held by Fidson Healthcare, with status Expired — the registration ran out in October 2023 and had not been renewed when our copy was taken. Listings can lag renewals, so confirm the current status on the official Greenbook. Several other iron products are recorded Active in our copy, including Fesulf, Ferobin, Ferrolab 12 and MeCure's Blood Tone.

### Is ferrous sulphate the same as ferrous fumarate or ferrous gluconate?

They are the same iron in different packaging. Each 'ferrous' product is iron (Fe2+) bonded to a different partner molecule to form a salt — sulfate, fumarate, or gluconate. Once dissolved, your body absorbs the same elemental iron from all of them, and all three treat and prevent iron deficiency anaemia. The practical difference is how much actual iron each milligram of salt carries: ferrous fumarate is about 33% elemental iron (200 mg gives ~65 mg iron), ferrous sulfate about 20% (300 mg gives ~60 mg iron), and ferrous gluconate about 12% (300 mg gives ~35 mg iron). That is why similar-looking strengths on different packs can deliver quite different amounts of iron, and why prescribers dose in elemental iron — typically 60–65 mg one to three times daily for treatment. Ferrous gluconate's reputation for being gentler on the stomach is largely this arithmetic: less iron per tablet. If you switch between brands that use different salts, match the elemental iron rather than the salt milligrams — a pharmacist can do this in a glance.

### What is the difference between 'blood tonic' and iron tablets?

In Nigeria, 'blood tonic' is the popular term used to describe iron supplements and haematinic formulations. There is no fundamental difference — blood tonics like Ranferon, Astyfer, and Chemiron are essentially iron supplements that also contain other nutrients such as folic acid, Vitamin B12, zinc, and Vitamin C that support blood formation. Simple ferrous sulfate tablets (such as Emzor Ferrous Sulfate) provide iron alone without the additional nutrients. Combination products (blood tonics) are popular because they provide multiple blood-building nutrients in a single capsule, which is convenient. Both are effective for treating iron deficiency anaemia, though your pharmacist or doctor can advise which is more appropriate for your specific situation.

### Why does iron turn my stool black?

Black or very dark stools are a completely normal and harmless side effect of taking iron supplements. This discolouration occurs because not all the iron in the tablet is absorbed by your body — the unabsorbed iron passes through your digestive system and reacts with substances in the gut to produce a dark colour. This is not a cause for concern and does not mean anything is wrong. However, if your stools are not just dark but also tarry, sticky, or have a very foul smell, or if you see red blood in your stool, you should see a doctor as this could indicate gastrointestinal bleeding rather than a normal iron side effect.

### When is the best time to take iron tablets?

Iron is best absorbed when taken on an empty stomach, ideally 30 minutes to 1 hour before a meal or 2 hours after eating. Taking it with a glass of water and a Vitamin C tablet or orange juice significantly boosts absorption. However, many Nigerians find that taking iron on an empty stomach causes nausea and stomach discomfort. If this happens to you, it is perfectly acceptable to take it with a light meal — you may absorb slightly less iron, but you are more likely to take it consistently, which matters more in the long run. Avoid taking iron with tea, coffee, milk, or yoghurt as these significantly reduce absorption. Also avoid taking iron at the same time as calcium supplements or antacids.

### How long do I need to take iron tablets to treat anaemia?

For iron deficiency anaemia, you typically need to take iron supplements for at least 3 to 6 months. Most people start to feel better (less fatigue, more energy) within 2 to 4 weeks of starting treatment, and blood tests may show improvement within 6 to 8 weeks. However, it is crucial to continue taking iron for at least 3 months after your haemoglobin levels have returned to normal, as this allows your body to fully replenish its iron stores. Stopping too early is a very common mistake in Nigeria and often leads to the anaemia returning. During pregnancy, iron is typically taken throughout the entire pregnancy and for at least 3 months after delivery. Your doctor or pharmacist will advise on the appropriate duration for your situation.

## Sources

- NAFDAC Greenbook (official register of approved products in Nigeria)
- WHO Model List of Essential Medicines
- British National Formulary (BNF)
- Nigerian Standard Treatment Guidelines (Federal Ministry of Health)