Key Facts
- Drug Class
- Iron supplement (haematinic)
- Prescription
- Over the counter
- NAFDAC Status
- NAFDAC Registered
- Forms
- Tablet, Syrup, Drops
- Price Range
- ₦200 - ₦5,000
- WHO Essential
- Yes
What is Ferrous Sulfate?
Ferrous sulfate is an iron supplement used to prevent and treat iron deficiency anaemia, a condition that is alarmingly prevalent in Nigeria. According to health surveys, over 60% of Nigerian children under five and approximately 50% of pregnant women suffer from some degree of anaemia, with iron deficiency being the most common cause. In everyday Nigerian language, iron supplements are widely referred to as 'blood tonic' or 'blood builder,' and this term is so deeply embedded in local healthcare vocabulary that many Nigerians will walk into a pharmacy and ask specifically for 'blood tonic' rather than iron tablets. From the busy pharmacies of Ikeja and Surulere in Lagos to health centres in Maiduguri and Sokoto, ferrous sulfate and its related iron formulations are among the most frequently dispensed supplements in the country.
Iron is an essential mineral that the body needs to produce haemoglobin, the protein in red blood cells responsible for carrying oxygen from the lungs to every tissue and organ in the body. When iron levels are low, the body cannot produce enough healthy red blood cells, leading to anaemia — a condition characterised by fatigue, weakness, pale skin and nails, shortness of breath, dizziness, and reduced ability to concentrate. In Nigeria, iron deficiency anaemia is driven by multiple factors including malaria (which destroys red blood cells), hookworm infections (common in rural areas), poor dietary iron intake, heavy menstrual bleeding in women, and the increased iron demands of pregnancy and breastfeeding. Ferrous sulfate provides elemental iron that the body can use to restore haemoglobin levels and red blood cell production.
Ferrous sulfate is listed on the WHO Essential Medicines List and is a cornerstone of maternal and child health programmes in Nigeria. It is available in several forms including standard tablets, combination capsules (which include folic acid, Vitamin B12, zinc, and other nutrients), syrups for children, and drops for infants. Some of the most popular brands in Nigeria include Ranferon (arguably the most recognised blood tonic brand in the country), Astyfer, Chemiron, and Ferobin, all of which are combination haematinic formulations. The locally manufactured Emzor Ferrous Sulfate provides a more affordable, straightforward iron tablet option. These products are available without a prescription from pharmacies and patent medicine stores across all 36 states and the Federal Capital Territory.
What is Ferrous Sulfate used for?
In Nigeria, Ferrous Sulfate is commonly used for:
- Treatment of iron deficiency anaemia — the most common type of anaemia in Nigeria, causing fatigue, weakness, pallor, and reduced physical and mental performance
- Prevention of anaemia during pregnancy, when iron requirements increase significantly to support the growing baby and expanded blood volume — routinely prescribed at every antenatal clinic in Nigeria
- Recovery from blood loss due to heavy menstrual periods (menorrhagia), which affects many Nigerian women and is a leading cause of anaemia in women of reproductive age
- Supplementation for children with nutritional anaemia, particularly in areas where dietary iron intake is inadequate or where malaria and hookworm infections are common
- Supporting recovery from anaemia caused by malaria, which destroys red blood cells and is endemic across much of Nigeria
- Post-surgical and post-partum recovery when blood loss has occurred and the body needs to rebuild its iron stores and red blood cell count
Dosage
IMPORTANT
Always follow your doctor's or pharmacist's instructions. The information below is for general reference only.
Adults
For treatment of iron deficiency anaemia: 200mg ferrous sulfate (containing approximately 65mg of elemental iron) two to three times daily. For prevention in pregnancy: 200mg once or twice daily, commonly taken alongside folic acid. Combination products like Ranferon and Chemiron are typically taken as one capsule once or twice daily depending on the severity of anaemia and the specific product.
Children
Children aged 6-12 years: 200mg ferrous sulfate once daily. Children aged 2-5 years: Iron syrup is preferred — typically 2.5ml to 5ml of ferrous sulfate syrup (25mg elemental iron per 5ml) once or twice daily. Infants from 6 months: Iron drops as directed by a paediatrician, usually 0.5ml to 1ml daily. Dosing should be based on the child's weight and severity of anaemia — always consult a healthcare provider for children.
Elderly
Standard adult doses apply, but elderly individuals should start with a lower dose (200mg once daily) and increase as tolerated, as they are more prone to constipation and stomach upset from iron supplements. Elderly patients with chronic kidney disease or other conditions should have their iron supplementation guided by a doctor.
Iron is best absorbed on an empty stomach, ideally taken 30 minutes to 1 hour before meals. However, if it causes stomach upset, it can be taken with a light meal. Taking iron with Vitamin C (such as orange juice or a Vitamin C tablet) significantly enhances absorption. Avoid taking iron with tea, coffee, milk, or calcium supplements as these reduce absorption. Do not take iron tablets at the same time as antacids, tetracycline antibiotics, or ciprofloxacin — space them at least 2 hours apart.
Side Effects
Common side effects
- •Black or dark-coloured stools — this is completely normal and harmless, caused by unabsorbed iron, but can be alarming to patients who are not warned beforehand
- •Constipation — one of the most common complaints, especially in pregnant women already prone to constipation
- •Nausea and stomach cramps, particularly when taken on an empty stomach
- •Metallic taste in the mouth
- •Temporary staining of teeth with liquid iron preparations (can be minimised by using a straw or dropper)
Serious side effects — seek medical help immediately
- Iron overdose (iron poisoning), which is a medical emergency especially in children — symptoms include severe vomiting, bloody diarrhoea, abdominal pain, and can be fatal if untreated
- Severe allergic reaction including rash, swelling, and difficulty breathing (rare with oral forms)
- Iron overload (haemosiderosis) from chronic excessive supplementation, which can damage the liver, heart, and pancreas
- Severe constipation or bowel obstruction in rare cases, particularly in elderly patients
When to see a doctor
Seek immediate medical attention if a child accidentally swallows iron tablets, as iron poisoning can be fatal in children. Also see a doctor if you experience severe stomach pain, vomiting blood, bloody or tarry stools beyond the normal dark discolouration, persistent severe constipation, or any signs of allergic reaction. If you are taking iron for anaemia and do not feel better after 4-6 weeks of treatment, consult your doctor as further investigation may be needed.
Warnings & Precautions
Do not take Ferrous Sulfate if you have:
- Do not take if you have haemochromatosis (iron overload disorder) or haemosiderosis, as additional iron supplementation could be dangerous
- Not recommended for people with peptic ulcer disease or inflammatory bowel disease (ulcerative colitis, Crohn's disease) without medical supervision, as iron can worsen these conditions
- Do not give iron supplements intended for adults to children — accidental iron overdose is a leading cause of fatal poisoning in children under 6 years
- Avoid in patients receiving repeated blood transfusions, as these already increase iron levels significantly
Drug interactions
- •Tetracycline and doxycycline antibiotics — iron significantly reduces the absorption of these antibiotics; space doses at least 2-3 hours apart
- •Ciprofloxacin and other fluoroquinolone antibiotics — iron reduces their absorption and effectiveness; take at least 2 hours before or 4 hours after iron
- •Antacids (aluminium, magnesium, calcium-based) — reduce iron absorption; space at least 2 hours apart
- •Levothyroxine (thyroid medication) — iron reduces its absorption; take at least 4 hours apart
- •Tea, coffee, and dairy products — the tannins in tea and coffee and the calcium in dairy significantly reduce iron absorption; avoid consuming these within 1-2 hours of taking iron
Pregnancy & Breastfeeding
Iron supplementation is strongly recommended during pregnancy and is a standard component of antenatal care in Nigeria. The WHO recommends daily iron and folic acid supplementation for all pregnant women to prevent anaemia, which is associated with increased risk of maternal and infant mortality. Ferrous sulfate is safe during pregnancy and breastfeeding at recommended doses. Most Nigerian antenatal clinics prescribe iron from the first antenatal visit and continue throughout pregnancy and for at least 3 months after delivery. Small amounts of iron pass into breast milk, but this is beneficial for the breastfeeding infant and does not cause harm.
Brands of Ferrous Sulfate in Nigeria
5 brands available in Nigeria.
| Brand Name | Manufacturer | Strength | Form | NAFDAC Reg. No. |
|---|---|---|---|---|
| Ranferon | Ranbaxy (Sun Pharmaceutical) | Ferrous fumarate 305mg + Folic acid 0.75mg + Zinc 22.5mg + B12 7.5mcg | Capsule | |
| Astyfer | Astrophia Pharma | Iron 50mg + Folic acid 0.5mg + B12 + other haematinics | Capsule | 04-2623 |
| Chemiron | Chemiron International | Iron + Folic acid + B12 + Vitamin C | Capsule | |
| Emzor Ferrous Sulfate | Emzor Pharmaceutical Industries | 200mg | Tablet | |
| Ferobin | Vitabiotics | Iron 20mg + Folic acid + B12 + Zinc | Capsule | 04-9722 |
How to Verify Your Ferrous Sulfate is Genuine
- 1Confirm that the product displays a valid NAFDAC registration number — all iron supplements sold in Nigeria must be NAFDAC-registered
- 2Verify the NAFDAC number using the official NAFDAC website (www.nafdac.gov.ng) or the NAFDAC mobile verification app available on Android and iOS
- 3Purchase iron supplements only from licensed pharmacies or accredited patent medicine stores — counterfeit haematinics have been intercepted by NAFDAC in the past
- 4For popular brands like Ranferon, Astyfer, and Chemiron, check for intact security seals, proper branding, batch numbers, and consistent packaging quality
- 5Check the expiry date before purchase and ensure the packaging is not damaged, faded, or showing signs of tampering
- 6Be cautious of unusually cheap iron supplements being sold in open markets like Idumota, Onitsha Main Market, or Head Bridge Market — significantly below-market prices often indicate counterfeit products
Ferrous Sulfate Price in Nigeria
Ferrous Sulfate prices in Nigeria typically range from ₦200 to ₦5,000 per pack, depending on the brand, strength, and where you buy it.
₦200 – ₦5,000
per pack
Prices vary by location and vendor. Last updated: 2026-02-01
Where to Buy
Purchase Ferrous Sulfate only from licensed pharmacies and verified distributors. Avoid buying medicines from unverified sources, roadside vendors, or unregistered market stalls.
Frequently Asked Questions
Sources
- •NAFDAC Greenbook — National Agency for Food and Drug Administration and Control registered products database
- •WHO Model List of Essential Medicines (23rd List, 2023)
- •British National Formulary (BNF)
- •Nigerian Standard Treatment Guidelines