Trihexyphenidyl — known throughout Nigeria as benzhexol, and abroad as Artane — is an anticholinergic that restores the balance between two chemical signals in the brain's movement circuits. When dopamine activity falls, acetylcholine activity becomes relatively dominant, and the result is tremor, muscle stiffness and slowness. Blocking some of that acetylcholine signal restores the balance and the movements ease.
In the NAFDAC register
27 registered products
from 27 registration holders
What it costs online
Price varies — check with a pharmacy. This drug has not yet appeared in our fortnightly sampling of Nigerian online pharmacies.
Brands of Trihexyphenidyl in Nigeria
Comes as
- Tablet5 mg· 20 makers
Those 27 products from 27 registration holders, counted in our October 2026 copy of the register, include combination products and older listings; below are the most common brands.
| Brand Name | Manufacturer | Strength | Form | NAFDAC Reg. No. |
|---|---|---|---|---|
| EGMP Benzhexol Tablets | Evergreen Morning Star Pharmaceutical Ind. Ltd | 5mg | Tablet | A11-100502 |
| Tekaxol Tablets | Teka Pharmaceutical Co. Ltd | 5mg | Tablet | A4-100439 |
| Oxazol-5 Tablet | New Heights Pharmaceuticals Ltd | 5mg | Tablet | A4-6110 |
| Axzol Tablets | Phinifarms Pharmaceutical Limited | 5mg | Tablet | B4-0153 |
Trihexyphenidyl Price in Nigeria
Trihexyphenidyl prices in Nigeria vary by brand, strength, and where you buy it. Confirm the current price with a licensed pharmacy, and always check the product is NAFDAC-registered before you pay.
We show a price here once it appears in our monthly sampling of Nigerian online pharmacies (MedPlus, HealthPlus), or when we have a reliable market figure. For now, confirm the current price directly with a licensed pharmacy.
How to Verify Your Trihexyphenidyl is Genuine
- 1Check the NAFDAC number on the pack — EGMP Benzhexol carries A11-100502 and Tekaxol carries A4-100439 in our copy of the register.
- 2Other registered products include Oxazol-5 (A4-6110) and Axzol (B4-0153).
- 3Confirm any brand with our NAFDAC checker — around twenty-one companies hold active registrations, so a genuine benzhexol should be findable in the register.
- 4Almost all registered products are 5mg tablets. If you were prescribed a smaller dose, ask the pharmacist how to divide it accurately rather than guessing.
- 5Buy from a registered pharmacy. Benzhexol is misused at high doses in some settings, which makes loose tablets sold outside pharmacies a category worth avoiding.
Where to Buy
Buying Trihexyphenidyl wholesale, by the carton
Cartons of trihexyphenidyl are bought at Nigeria's open drug markets: Idumota Market in Lagos, Ariaria Market in Aba, Ogbogwu Market in Onitsha and Sabon Gari Market in Kano. Each guide says where the market is and how to buy there safely; where we list sellers, they are named.
- Idumota Market, Lagos · wholesale sellers in Idumota Market
- Ariaria Market, Aba
- Ogbogwu Market, Onitsha
- Sabon Gari Market, Kano
No shop we list has Trihexyphenidyl on its confirmed product list yet — the market guides still tell you where the trade happens and how to buy there safely.
Which one are you?
I'm buying trihexyphenidyl
Tell us what you need and the quantity, and we'll connect you with a verified, NAFDAC-registered source. Free, no obligation.
I sell trihexyphenidyl
Get a free page where buyers look for them: your products, your number, how to find your shop. Independent of NAFDAC and government. Nothing goes live until you have seen it and approved it. Why list? →
Wherever you buy, buy only from licensed pharmacies and verified distributors — not roadside vendors — and verify the pack's NAFDAC registration before you pay. Buying Trihexyphenidyl in bulk or for resale? See how to buy medicines in bulk in Nigeria safely.
Need Trihexyphenidyl in bulk, or can't find it near you?
Tell us what you need and we'll connect you with a verified, NAFDAC-registered source.
What is Trihexyphenidyl?
It was developed for Parkinson's disease, but that is not mostly what it does here. In Nigerian practice, benzhexol is overwhelmingly prescribed alongside antipsychotic medicines such as haloperidol and chlorpromazine, to control the movement side effects those drugs cause. That pairing is so routine that the two are often dispensed together as a matter of course.
Our copy of the NAFDAC register shows around twenty active registrations from about twenty companies — a completely flat field, every company holding a single 5mg tablet, most of them plainly named Benzhexol. It is cheap and widely available. It is also more habit-forming than its reputation suggests: at higher doses it produces euphoria and hallucinations, and it is misused in some settings, which is a reason it should be prescribed deliberately rather than reflexively.
What is Trihexyphenidyl used for?
In Nigeria, Trihexyphenidyl is commonly used for:
- Movement side effects of antipsychotic medicines — tremor, stiffness, restlessness — its dominant use in Nigeria
- Acute dystonic reactions: sudden painful spasms of the neck, jaw, tongue or eyes, often within days of starting an antipsychotic
- Drug-induced parkinsonism
- Parkinson's disease, as an adjunct where tremor dominates, usually in younger patients
- Not effective for tardive dyskinesia — the late-onset involuntary movements — which it can make worse
Dosage
IMPORTANT
Always follow your doctor's or pharmacist's instructions. The information below is for general reference only.
Adults
Treatment starts low, typically 1mg on the first day, increasing gradually to a usual range of 5mg to 15mg daily in divided doses depending on response and tolerance. It is taken with or after food. Where it is given to prevent dystonia at the start of antipsychotic treatment, the course is often intended to be short — the movement side effects frequently settle after the first weeks — and it should be reviewed rather than simply continued for years.
Children
Trihexyphenidyl is used in children only under specialist supervision, most often for dystonia, and dosed by weight. Children are more sensitive to its effects on the brain.
Elderly
Older adults tolerate anticholinergics poorly. Confusion, memory impairment, constipation, urinary retention and falls are all more likely, and the cumulative anticholinergic burden of several such medicines together is a recognised contributor to cognitive decline. Where an older person needs treatment for drug-induced parkinsonism, reducing or changing the antipsychotic is usually the better answer.
Do not stop benzhexol suddenly after long use — the movement symptoms it was suppressing can rebound sharply, and there is a withdrawal syndrome of its own. If it is to be stopped, it is tapered. The more important question is whether it should be prescribed indefinitely at all: taking a second drug permanently to manage the side effects of the first is worth reviewing with a psychiatrist, because a change of antipsychotic or a dose reduction sometimes removes the need entirely.
Side Effects
General information for a reader holding a pack, not a substitute for a doctor or pharmacist. If something on the serious list is happening, seek care now.
Common side effects
- •Dry mouth — very common and often the limiting factor
- •Blurred vision
- •Constipation
- •Difficulty passing urine
- •Dizziness and drowsiness
Serious side effects — seek medical help immediately
- Confusion, memory impairment, agitation or hallucinations, particularly in older adults
- Acute angle-closure glaucoma — sudden eye pain with blurred vision and halos around lights
- Complete urinary retention, more likely in men with prostate enlargement
- Heat stroke — anticholinergics reduce sweating, which matters in Nigerian heat
- Rapid heartbeat
- Misuse and dependence at higher doses, with euphoria and hallucinations
When to see a doctor
Seek urgent care for sudden eye pain with blurred vision or halos, for an inability to pass urine, and for confusion or hallucinations that are new. In hot weather, seek help for a high body temperature with hot dry skin and no sweating. Report worsening or new involuntary movements, since those may be tardive dyskinesia, which benzhexol does not treat and can aggravate.
Warnings & Precautions
General information for a reader holding a pack, not a substitute for a doctor or pharmacist. If something on the serious list is happening, seek care now.
Do not take Trihexyphenidyl if you have:
- Narrow-angle glaucoma
- Urinary retention or significant prostate enlargement
- Bowel obstruction, or severely reduced gut motility
- Myasthenia gravis
- Known hypersensitivity to trihexyphenidyl
Drug interactions
- •Other anticholinergic medicines — including promethazine, amitriptyline and some antipsychotics — the effects add up, and the total burden is what causes confusion and retention
- •Alcohol and sedatives — additive drowsiness
- •Metoclopramide — its effect on the gut is opposed by anticholinergics
- •Levodopa — dose adjustments may be needed in Parkinson's disease
- •Medicines that raise body temperature or reduce sweating — combined heat risk
Pregnancy & Breastfeeding
Safety in pregnancy is not well established and trihexyphenidyl is used only where clearly necessary. It may reduce milk production and passes into breast milk. Anyone taking it alongside an antipsychotic and planning a pregnancy should review the whole regimen with a psychiatrist rather than stopping either drug alone.
Related Resources for Trihexyphenidyl
Guides, articles, and tools related to Trihexyphenidyl and other mental health medicines in Nigeria.
Frequently Asked Questions
Sources
- •NAFDAC Greenbook — the official database of all products registered with Nigeria's National Agency for Food and Drug Administration and Control. Brand-level NAFDAC numbers for Trihexyphenidyl on this page were cross-referenced against the Greenbook.
- •British National Formulary (BNF) dosing and interaction guidance for Trihexyphenidyl.
- •Nigerian Standard Treatment Guidelines (Federal Ministry of Health).
Daily puzzle: Meddle — pair five brands with their medicines. New game at midnight.