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Adapalene

Topical retinoid (acne treatment) · Over the counter · Gel

Adapalene has 2 active NAFDAC registrations in our October 2026 copy of the register, from 2 registration holders.

Also known as: Differin, Adapalene gel, Epiflin

  • NAFDAC-registered brands

Ogbogwu is a reference directory quoting the NAFDAC register. We do not sell, dispense or prescribe medicines, and nothing here replaces a doctor or pharmacist.

Adapalene

~₦25,140

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Adapalene is a topical retinoid — a vitamin-A-derived gel applied to the skin to treat acne. It works by normalising how skin cells shed inside pores, so blackheads and whiteheads stop forming, and by calming the inflammation that turns blocked pores into angry pimples. In Nigeria it sells as a 0.1% gel; internationally the best-known brand is Differin, and NAFDAC-registered equivalents here include Epiflin and Norbacare.

In the NAFDAC register

2 registered products

from 2 registration holders

In force · October 2026 copy2 active
Where madenone in Nigeria · 2 imported
China1
India1
See all 2 registered brands →

What it costs online

about ₦25,140

0% since September 2026 · like-for-like

Sampled from 3 listings across MedPlus and Supermart.ng · October 2026

Full price breakdown →

Brands of Adapalene in Nigeria

Those 2 products from 2 registration holders, counted in our October 2026 copy of the register, include combination products and older listings; below are the most common brands.

Adapalene Price in Nigeria

As of October 2026, Adapalene sells for about ₦25,140 online in Nigeria (₦7,725–₦28,350) at MedPlus and Supermart.ng. The online price is roughly unchanged since September 2026. Open-market prices (e.g. Idumota, Ogbogwu) are often lower.

Online retail (sampled)

Same medicine throughout — every listing contains Adapalene. The difference is brand and pack size.

median ₦25,140 · 3 listings

CheapestDifferin Gel 0.1% 30 g(Supermart.ng)

₦7,725

PriciestDIFFERIN GEL 0.1% 45G(MedPlus)

₦28,350

3 listings across MedPlus + Supermart.ng — brands and pack sizes vary · October 2026.

Unchanged since September 2026.

How to Verify Your Adapalene is Genuine

  1. 1Check the tube and carton for the NAFDAC registration number — Epiflin gel carries A4-101036, Norbacare A4-100668
  2. 2Enter the number in our free NAFDAC checker and confirm it matches the product and maker printed on the pack
  3. 3Buy from a registered pharmacy — imported 'Differin' with no NAFDAC number on the pack cannot be verified here
  4. 4Be wary of any acne product that promises visible results in days: genuine retinoids take weeks, and the products that promise otherwise usually contain undeclared steroids

Where to Buy

Buying Adapalene wholesale, by the carton

Cartons of adapalene are bought at Nigeria's open drug markets: Idumota Market in Lagos, Ogbogwu Market in Onitsha, Ariaria Market in Aba and Sabon Gari Market in Kano. Each guide says where the market is and how to buy there safely; where we list sellers, they are named.

No shop we list has Adapalene on its confirmed product list yet — the market guides still tell you where the trade happens and how to buy there safely.

Which one are you?

I'm buying adapalene

Tell us what you need and the quantity, and we'll connect you with a verified, NAFDAC-registered source. Free, no obligation.

I sell adapalene

Get a free page where buyers look for them: your products, your number, how to find your shop. Independent of NAFDAC and government. Nothing goes live until you have seen it and approved it. Why list? →

See a listed shop: Blessed Michael Pharmacy → · or sign up yourself →

Wherever you buy, buy only from licensed pharmacies and verified distributors — not roadside vendors — and verify the pack's NAFDAC registration before you pay. Buying Adapalene in bulk or for resale? See how to buy medicines in bulk in Nigeria safely.

Need Adapalene in bulk, or can't find it near you?

Tell us what you need and we'll connect you with a verified, NAFDAC-registered source.

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What is Adapalene?

It is a treatment for the coming weeks' skin, not tonight's pimple: adapalene prevents new spots from forming, and the visible payoff arrives over 8–12 weeks of nightly use. Many people's skin looks slightly worse in weeks 2–4 before it looks better — a known settling-in effect, not a sign the gel is fake or failing.

Unlike the steroid combination creams widely sold in Nigerian markets, adapalene is actually meant for acne. Triple- and quadruple-action steroid creams make acne worse with continued use; adapalene is the evidence-backed alternative for pimples.

What is Adapalene used for?

In Nigeria, Adapalene is commonly used for:

  • Mild to moderate acne — blackheads, whiteheads and inflamed pimples on the face, chest or back
  • Keeping acne-prone skin clear with continued nightly use
  • As the retinoid half of combination acne treatment (with benzoyl peroxide or an oral antibiotic) for more severe acne

Dosage

IMPORTANT

Always follow your doctor's or pharmacist's instructions. The information below is for general reference only.

Adults

Apply a thin layer to the whole acne-prone area (not just individual spots) once daily at night, on clean, dry skin. A pea-sized amount covers the face. Wash hands after applying. Expect 8–12 weeks of nightly use before judging whether it works; do not apply more often to speed it up — that only increases irritation.

Children

Suitable for teenagers with acne (12 years and older). Not for younger children except on a doctor's advice.

Elderly

Acne is uncommon after middle age — if new 'acne' appears later in life, see a pharmacist or doctor to check what it actually is before treating it.

Use a moisturiser (adapalene dries the skin, especially in the first weeks) and sunscreen or sun avoidance — treated skin burns more easily. Do not apply to broken skin, eczema or sunburn, and keep it away from eyes, lips and nostrils.

Side Effects

General information for a reader holding a pack, not a substitute for a doctor or pharmacist. If something on the serious list is happening, seek care now.

Common side effects

  • •Dryness, peeling, mild burning or stinging where applied — usually worst in weeks 1–4, then settles
  • •Redness and skin irritation
  • •Temporary worsening of breakouts in the first month (the settling-in flare)
  • •Increased sensitivity to sunlight

Serious side effects — seek medical help immediately

  • Severe irritation, blistering or swelling — stop and see a pharmacist or doctor
  • Allergic reaction: spreading rash, itching, swelling of the face

When to see a doctor

See a pharmacist or doctor if irritation is severe or not settling after the first month, if there is no improvement at all after 12 weeks of nightly use, or if acne is deep, scarring or cystic — that grade needs more than a gel.

Warnings & Precautions

General information for a reader holding a pack, not a substitute for a doctor or pharmacist. If something on the serious list is happening, seek care now.

Do not take Adapalene if you have:

  • Known allergy to adapalene or any component of the gel
  • Broken, eczematous or sunburnt skin
  • Pregnancy — as a retinoid, adapalene is not recommended during pregnancy; tell your pharmacist if you are pregnant or planning to be

Drug interactions

  • •Other drying or peeling products (strong soaps, alcohol-based toners, salicylic acid scrubs) — the irritation adds up; introduce one thing at a time
  • •Waxing treated skin can tear it — avoid waxing areas under treatment

Pregnancy & Breastfeeding

Not recommended in pregnancy: although very little topical adapalene reaches the bloodstream, retinoids as a class are avoided while pregnant. While breastfeeding, avoid applying it on or near the chest and use only on a pharmacist's or doctor's advice.

Related Resources for Adapalene

Guides, articles, and tools related to Adapalene and other dermatology medicines in Nigeria.

Frequently Asked Questions

Sources

  • •NAFDAC Greenbook — the official database of all products registered with Nigeria's National Agency for Food and Drug Administration and Control. Brand-level NAFDAC numbers for Adapalene on this page were cross-referenced against the Greenbook.
  • •British National Formulary (BNF) dosing and interaction guidance for Adapalene.
  • •Nigerian Standard Treatment Guidelines (Federal Ministry of Health).

Last updated: 1 October 2026

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