Mifepristone is an antiprogestogen: it blocks progesterone, the hormone that keeps the lining of the womb in place during pregnancy. Given first, it loosens the pregnancy from the womb wall and softens the cervix; misoprostol, given one to two days later, then makes the womb contract and empty. The two together are the World Health Organization's standard regimen for medical management of early pregnancy loss and of abortion where it is lawful, and both are on the WHO Model List of Essential Medicines.
In the NAFDAC register
4 registered products
from 4 registration holders
What it costs online
Price varies — check with a pharmacy. This drug has not yet appeared in our fortnightly sampling of Nigerian online pharmacies.
Brands of Mifepristone in Nigeria
Those 4 products from 4 registration holders, counted in our October 2026 copy of the register, include combination products and older listings; below are the most common brands.
- Mifepristone 200 mg + misoprostol 4 × 200 mcg · Combipack · B4-6871
- Divine Care Pharmaceutical LtdMifepristone 200 mg + misoprostol 4 × 200 mcg · Kit · B4-9892
| Brand Name | Manufacturer | Strength | Form | NAFDAC Reg. No. |
|---|---|---|---|---|
| Mariprist | MSI Nigeria Reproductive Choices Ltd/Gte | Mifepristone 200 mg + misoprostol 4 × 200 mcg | Combipack | B4-6871 |
| Evabon | Aurora Pharmaceuticals Nig Ltd | Mifepristone 200 mg + misoprostol 4 × 200 mcg | Tablet | A4-101738 |
| Mifabon Combipack | Divine Care Pharmaceutical Ltd | Mifepristone 200 mg + misoprostol 4 × 200 mcg | Kit | B4-9892 |
| Cezera | Dony-Triumph and Company Nigeria Limited | 200 mg | Tablet | A4-7784 |
Mifepristone Price in Nigeria
Our sampled online pharmacies hold no mifepristone listing, so we quote no price: the registered products are combipacks supplied through hospitals, gynaecology clinics and reproductive-health organisations rather than sold off the shelf. Cost is usually part of a facility's fee for managing a miscarriage or incomplete abortion, and a pack offered loose, cheaply, by a street or online seller is the pack to refuse.
We show a price here once it appears in our monthly sampling of Nigerian online pharmacies (MedPlus, HealthPlus), or when we have a reliable market figure. For now, confirm the current price directly with a licensed pharmacy.
How to Verify Your Mifepristone is Genuine
- 1Check the pack for a NAFDAC registration number. In our copy of the register, Mariprist combipack carries B4-6871 and Evabon A4-101738, both Active
- 2Mifabon Combipack (B4-9892) and the single Cezera 200 mg tablet (A4-7784) are recorded as Expired — a pack carrying either number should be confirmed on the official Greenbook before it is dispensed
- 3Enter the number in our free NAFDAC checker and confirm the product name, holder and composition (one 200 mg mifepristone tablet, four 200 mcg misoprostol tablets) match the pack
- 4This medicine is dispensed in facilities. A combipack sold loose by a street vendor, a social-media seller or a patent-medicine shop — the setting in which most counterfeit and expired packs change hands — should be refused regardless of what the number says
Where to Buy
Mifepristone is dispensed in hospitals, gynaecology clinics and reproductive-health facilities, for managing a miscarriage that has not completed and for post-abortion care. Abortion is a criminal offence in Nigeria except to save the woman's life, and a pack sold outside a facility is sold outside the law and outside any safety net for the heavy bleeding it can cause. Ogbogwu therefore lists no sellers for it and takes no requests for it. If you are bleeding in early pregnancy or in pain after an abortion, go to a hospital. Check any pack you are offered against the register before you accept it.
What is Mifepristone?
In Nigeria mifepristone is registered almost entirely as a combipack with misoprostol: one 200 mg mifepristone tablet packed with four 200 mcg misoprostol tablets. Our copy of the NAFDAC register holds two such packs with Active registrations — Mariprist, held by MSI Nigeria Reproductive Choices, and Evabon, held by Aurora Pharmaceuticals — and two older entries, Mifabon and the single-ingredient Cezera 200 mg tablet, whose registrations have expired. It is a prescription-only medicine supplied through hospitals, gynaecology clinics and reproductive-health organisations, not an over-the-counter product.
The law matters here. Abortion in Nigeria is a criminal offence under both the Criminal Code (southern states) and the Penal Code (northern states) except to save the life of the woman, and this page does not advise anyone on obtaining one. What the register does establish is that mifepristone itself is lawfully registered, because it has lawful uses: managing a miscarriage that has not completed on its own, and post-abortion care, both of which Nigerian hospitals provide. Ogbogwu lists no sellers for it and takes no requests for it.
What is Mifepristone used for?
In Nigeria, Mifepristone is commonly used for:
- Missed miscarriage and incomplete miscarriage in the first trimester, with misoprostol, as an alternative to surgical evacuation
- Post-abortion care — completing the emptying of the womb after an incomplete or unsafe abortion, to prevent infection and bleeding
- Cervical preparation before some surgical gynaecological procedures
- Medical abortion, only where the law permits it and only under medical supervision
Dosage
IMPORTANT
Always follow your doctor's or pharmacist's instructions. The information below is for general reference only.
Adults
Always under a doctor who has confirmed by scan or examination that the pregnancy is inside the womb and estimated how far along it is. For early pregnancy loss and for medical abortion under 12 weeks, the WHO regimen is one 200 mg mifepristone tablet by mouth, followed 24 to 48 hours later by 800 mcg of misoprostol (the four 200 mcg tablets in the combipack) placed in the cheek, under the tongue or in the vagina as the clinician directs. Bleeding and cramping usually begin within a few hours of the misoprostol and the womb empties over the following one to two days. A follow-up visit or scan one to two weeks later confirms it is complete.
Children
Not applicable. Any pregnancy in a girl under 18 needs a doctor and, in Nigeria, the involvement of a hospital's gynaecology team.
Elderly
Not applicable.
Mifepristone is never a stand-alone treatment — without the misoprostol that follows it, the womb frequently does not empty. It does not work for an ectopic pregnancy (one outside the womb), which is a surgical emergency: this is why a scan or careful examination comes first. Women who are Rhesus-negative may need an anti-D injection. Pain relief with ibuprofen or paracetamol is normal and expected.
Side Effects
General information for a reader holding a pack, not a substitute for a doctor or pharmacist. If something on the serious list is happening, seek care now.
Common side effects
- •Cramping and period-like pain, often strong, for several hours after the misoprostol
- •Bleeding heavier than a period for a few hours, then lighter bleeding or spotting for one to two weeks
- •Nausea, vomiting, diarrhoea, headache, dizziness
- •Fever or chills for a few hours after misoprostol — usually from the misoprostol itself, not infection
Serious side effects — seek medical help immediately
- Heavy bleeding — soaking two or more large pads an hour for two hours in a row — needs urgent hospital care
- Fever above 38°C lasting more than 24 hours, foul-smelling discharge or worsening pain after the first day: possible infection or retained tissue
- Severe one-sided pain, fainting or shoulder-tip pain: a possible ectopic pregnancy, which these tablets do not treat
- Allergic reaction: rash, swelling of the face or lips, difficulty breathing
When to see a doctor
Go to a hospital the same day for heavy bleeding as described above, fainting, fever beyond the first day, severe or one-sided pain, or if no bleeding has started within 24 hours of taking the misoprostol. Attend the follow-up appointment even if everything seems fine — an incomplete miscarriage can be silent until it causes infection.
Warnings & Precautions
General information for a reader holding a pack, not a substitute for a doctor or pharmacist. If something on the serious list is happening, seek care now.
Do not take Mifepristone if you have:
- Suspected or confirmed ectopic pregnancy, or a pregnancy that has not been confirmed to be in the womb
- An intrauterine device (IUD) still in place — it must be removed first
- Chronic adrenal failure, or long-term corticosteroid treatment
- Bleeding disorders or treatment with blood-thinning medicines
- Inherited porphyria; known allergy to mifepristone or to prostaglandins (misoprostol)
- Anywhere the woman cannot reach emergency care for heavy bleeding within an hour or two
Drug interactions
- •Strong CYP3A4 inhibitors (ketoconazole, itraconazole, erythromycin, ritonavir) can raise mifepristone levels; strong inducers (rifampicin, carbamazepine, phenytoin, St John's wort) can lower them
- •Blood thinners (warfarin, rivaroxaban) and antiplatelets add to the bleeding risk
- •Long-term corticosteroids — mifepristone blocks their effect; doses may need adjusting
- •Non-steroidal painkillers such as ibuprofen do not reduce its effect and are the usual pain relief alongside it
Pregnancy & Breastfeeding
Mifepristone ends a pregnancy; it must never be taken by a woman who intends to continue one, and if a pregnancy continues after an incomplete course the risk of harm to the baby means specialist follow-up is essential. Small amounts pass into breast milk; WHO advice is that breastfeeding need not be interrupted, though some clinicians advise expressing and discarding milk for the first few hours after the dose.
Related Resources for Mifepristone
Guides, articles, and tools related to Mifepristone and other reproductive health medicines in Nigeria.
Frequently Asked Questions
Sources
- •NAFDAC Greenbook — the official database of all products registered with Nigeria's National Agency for Food and Drug Administration and Control. Brand-level NAFDAC numbers for Mifepristone on this page were cross-referenced against the Greenbook.
- •WHO Model List of Essential Medicines — Mifepristone is included in the WHO's list of essential medicines, meaning it is considered essential for basic healthcare needs.
- •British National Formulary (BNF) dosing and interaction guidance for Mifepristone.
- •Nigerian Standard Treatment Guidelines (Federal Ministry of Health).
Daily puzzle: Meddle — pair five brands with their medicines. New game at midnight.