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Clopidogrel

P2Y12 platelet inhibitor (thienopyridine) · Prescription only · Tablet · WHO essential

Also known as: Plavix, Ceruvin, Clopi-Denk

On this page

Clopidogrel is an antiplatelet medicine — a blood thinner in everyday language — taken once a day as a 75mg tablet to stop platelets clumping together and forming a clot. It is prescribed to people who have already had a heart attack, a stroke or a mini-stroke, who have had a stent placed in a coronary artery, or who have narrowed arteries in the legs. It is not a treatment for high blood pressure or cholesterol, though most people taking it are on medicines for those as well.

In the NAFDAC register

43 registered products

from 40 registration holders

In force24 active · 19 lapsed
Where made1 in Nigeria · 23 imported
India21
Bangladesh1
Nigeria1
Pakistan1
See all 43 registered brands

What it costs online

about ₦3,475

₦124 per tablet (tablet/capsule)

0% since July 2026 · like-for-like

Sampled from 4 listings across HealthPlus and MedPlus · September 2026

Full price breakdown →

Brands of Clopidogrel in Nigeria

Those 43 products from 40 registration holders include combination products and older listings; below are the most common brands.

See all 43 registered Clopidogrel brands

Clopidogrel Price in Nigeria

As of September 2026, Clopidogrel tablets sells for about ₦124 per tablet online in Nigeria (packs ₦1,940–₦5,100) across HealthPlus and MedPlus. The online price is roughly unchanged since July 2026. That figure is for Plagerine; 23 other clopidogrel brands are NAFDAC-registered and generic versions usually cost less. Open-market prices (e.g. Idumota, Ogbogwu) are often lower.

Online retail (sampled)

₦1,940 for 30 tablets

₦5,100 for 30 tablets

Same 75mg Clopidogrel — 2.6× the price for an identical pack, so the difference is the brand.

median ₦3,475 · 4 listings

CheapestPlagerine Clopidogrel 75mg Tablets x30(HealthPlus)

₦1,940

PriciestPLAGERINE 75MG * 30 TABS(MedPlus)

₦5,100

4 listings across HealthPlus + MedPlus — brands and pack sizes vary · September 2026.

tablets: about ₦124 per tablet (₦65₦170), from the 4 listings that state a pack size.

Unchanged since July 2026.

Clopidogrel price by brand

Each brand's own listings, as its page states them — the range above spans every brand and pack size.

How to Verify Your Clopidogrel is Genuine

  1. 1Check for a NAFDAC registration number on the pack — all clopidogrel sold legally in Nigeria carries one
  2. 2Verify the number in the NAFDAC Green Book or the NAFDAC verification app, and be particularly careful with imported brands
  3. 3Confirm the strength reads 75mg, which is the only strength registered in Nigeria for ongoing use
  4. 4Buy from a licensed pharmacy — this is a long-term prescription medicine and a reliable supplier matters more than a few naira
  5. 5Check the expiry date and that the blister is sealed and unbroken, with the batch number legible
  6. 6If you switch brands because of price or stock, tell your pharmacist so the change is recorded, and keep the pack until the new one is finished

Where to Buy

Buying Clopidogrel by the carton

Cartons are bought at Nigeria's four open drug markets. Each guide names the sellers there you can contact, and how to buy safely:

No shop we list has Clopidogrel on its confirmed product list yet — the market guides still tell you where the trade happens and how to buy there safely.

Wherever you buy, buy only from licensed pharmacies and verified distributors — not roadside vendors — and verify the pack's NAFDAC registration before you pay. Buying Clopidogrel in bulk or for resale? See how to buy medicines in bulk in Nigeria safely.

Need Clopidogrel in bulk, or can't find it near you?

Tell us what you need and we'll connect you with a verified, NAFDAC-registered source.

Request it
One tap, nothing to fill — it marks your state on our shortage map.

What is Clopidogrel?

It works differently from aspirin, which is why the two are sometimes given together. Aspirin blocks one route by which platelets are activated; clopidogrel blocks another, the P2Y12 receptor that responds to a signalling chemical called ADP. Using both at once is called dual antiplatelet therapy, and after a stent it is standard for a defined period — often six to twelve months — before dropping back to one. The period is a clinical decision, not a personal one.

Clopidogrel is a prodrug: it arrives inactive and the liver has to convert it, mainly through an enzyme called CYP2C19. That detail matters in practice, because some people carry a version of the enzyme that converts it poorly, and because certain other medicines — notably omeprazole and esomeprazole — get in the way of the conversion. Twenty-six clopidogrel products are currently registered with NAFDAC for the Nigerian market, most of them imported from India, with Avro Pharma's version made locally.

What is Clopidogrel used for?

In Nigeria, Clopidogrel is commonly used for:

  • Preventing a further heart attack, stroke or transient ischaemic attack in people who have already had one
  • Preventing clot formation inside a coronary stent, taken with aspirin for a period decided by the cardiologist
  • Acute coronary syndromes, usually started in hospital with a higher loading dose
  • Peripheral arterial disease, where narrowed leg arteries cause pain on walking
  • As an alternative antiplatelet for people who cannot take aspirin because of allergy, asthma or stomach problems

Dosage

IMPORTANT

Always follow your doctor's or pharmacist's instructions. The information below is for general reference only.

Adults

The usual dose is one 75mg tablet once a day, at the same time each day, with or without food. In hospital a higher loading dose of 300mg or 600mg is often given once at the start of treatment to work faster; that is a hospital decision and not something to repeat at home. After a stent, clopidogrel is normally taken alongside low-dose aspirin for a set period, then usually continued alone or replaced by aspirin — your cardiologist decides which.

Children

Clopidogrel is not used in children in ordinary practice. It has no established dose for common childhood conditions and is only used in specialist paediatric cardiology under close supervision.

Elderly

No dose reduction is needed for age alone, and older people gain the same protection. They do bleed more readily, however, so doctors watch for bruising, black stools and anaemia, and are careful about combining clopidogrel with other medicines that thin the blood.

Do not stop clopidogrel on your own. If you have a coronary stent, stopping early is genuinely dangerous — the stent can clot off suddenly, causing a heart attack — so any decision to pause it belongs to your cardiologist. Tell every dentist, surgeon and doctor that you take it before any procedure, because it usually needs to be stopped five to seven days before planned surgery, again only on advice. If you miss a dose, take it when you remember unless the next one is nearly due; never take two at once.

Side Effects

Common side effects

  • Bruising easily, and small cuts bleeding for longer than usual
  • Nosebleeds and bleeding gums
  • Indigestion, abdominal pain, diarrhoea or nausea
  • Headache and dizziness
  • Rash or itching

Serious side effects — seek medical help immediately

  • Bleeding from the gut: black tarry stools, vomiting blood or material resembling coffee grounds, or severe abdominal pain
  • Signs of bleeding in the brain: sudden severe headache, confusion, one-sided weakness, or loss of speech or vision
  • Heavy or prolonged bleeding from any site that does not settle with pressure
  • Thrombotic thrombocytopenic purpura, a rare but serious reaction causing unexplained bruising, tiny purple spots on the skin, fever, weakness or confusion — usually within the first two weeks
  • Severe allergic reaction with swelling of the face or throat, or a widespread blistering rash

When to see a doctor

Go to hospital immediately for black or tarry stools, vomiting blood, a sudden severe headache, or one-sided weakness. Seek same-day advice for unexplained bruising or pinpoint purple spots on the skin, particularly in the first fortnight of treatment. Report ordinary nosebleeds and gum bleeding to your doctor or pharmacist rather than stopping the tablet, and never stop it yourself if you have a stent — call your cardiologist's clinic instead.

Warnings & Precautions

Do not take Clopidogrel if you have:

  • Do not take if you have active bleeding, such as a bleeding stomach ulcer or bleeding within the brain
  • Do not take if you are allergic to clopidogrel or to related medicines such as prasugrel or ticagrelor
  • Avoid in severe liver disease, where both bleeding risk and drug handling are affected
  • Use with great caution if you have a recent head injury, recent surgery, or a known bleeding disorder

Drug interactions

  • Omeprazole and esomeprazole reduce clopidogrel's activation and may weaken its protection — pantoprazole or famotidine are the usual alternatives if stomach protection is needed
  • Warfarin and the newer anticoagulants greatly increase bleeding risk when combined and are only used together deliberately
  • Aspirin — a deliberate and common combination after a stent, but it does raise bleeding risk and should be for a defined period
  • Ibuprofen, diclofenac and other NSAIDs increase the risk of stomach bleeding
  • SSRI antidepressants such as fluoxetine and sertraline add to bleeding risk
  • Rifampicin increases clopidogrel's effect, while some antifungals and carbamazepine can reduce it

Pregnancy & Breastfeeding

There is limited safety information on clopidogrel in pregnancy, and it is generally avoided unless there is a clear and pressing reason. If you are taking clopidogrel and become pregnant or are planning to, tell your doctor promptly rather than stopping the tablet yourself — the right course depends on why you are on it, and stopping carries its own risk. It is not known how much passes into breast milk, so breastfeeding while taking clopidogrel is usually discouraged; discuss the alternatives with your doctor.

Related Resources for Clopidogrel

Guides, articles, and tools related to Clopidogrel and other blood thinners medicines in Nigeria.

Frequently Asked Questions

Sources

  • NAFDAC Greenbook — the official database of all products registered with Nigeria's National Agency for Food and Drug Administration and Control. Brand-level NAFDAC numbers for Clopidogrel on this page were cross-referenced against the Greenbook.
  • WHO Model List of Essential Medicines Clopidogrel is included in the WHO's list of essential medicines, meaning it is considered essential for basic healthcare needs.
  • British National Formulary (BNF) dosing and interaction guidance for Clopidogrel.
  • Nigerian Standard Treatment Guidelines (Federal Ministry of Health).

Last updated: 1 September 2026

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